calculate log-likilhood score of each gene based on reference expression profiles and return the centered score matrix
Usage
scoreGenesInRef(genes, ref_profiles, flag_center = TRUE)
Arguments
- genes
a vector of gene name to score
- ref_profiles
a gene X cell_type expression matrix for reference profiles
- flag_center
flag to center the score matrix per gene before return, default = TRUE
Value
loglik, a gene X cell_type matrix of centered loglik score for each gene