Given cell assignments (or posterior probabilities), estimate the mean profile of each cluster.
Usage
estimate_MeanProfile(counts, clust, s, bg)
Arguments
- counts
Counts matrix, cells X genes.
- clust
Vector of cluster assignments, or a matrix of probabilities of cells (rows) belonging to clusters (columns).
- s
Vector of scaling factors for each cell, e.g. as defined by cell area.
- bg
Expected background
Value
A matrix of cluster profiles, genes X clusters
Details
E step: estimate each cluster's mean profile (Ptolemy Estep function)
estimate each cluster's mean profile (Ptolemy Estep function)